Fig. 4. yps^JM2 rescues the osk mRNA localization defects of orb^mel/orb^F303 females. In wild-type ovaries, osk mRNA accumulates in the oocytes of young egg chambers (stages 1-7), is transiently localized to the anterior of the oocyte in stage-8 to early stage-9 egg chambers, and then becomes localized to the posterior pole of the oocyte by late 9. (A) Egg chambers from control (w¹¹¹⁸) ovaries. In the stage-10 egg chamber on the right, osk mRNA is localized at the posterior of the oocyte. (B) yps^JM2/yps^JM2egg chambers. osk mRNA accumulates normally in the oocytes of young-stage egg chambers on the left. In the stage-10 egg chamber in the center of the panel, osk mRNA is localized normally to the posterior pole of the oocyte. (C) orb^mel/orb^F303 egg chambers. In the stage-10 egg chamber in the center of the panel, osk mRNA is not localized at the posterior pole of the oocyte. (D) yps^JM2orb^mel/yps^JM2orb^F303egg chambers. In the stage-10 egg chamber on the right, osk mRNA is localized at the posterior pole of the oocyte, although its level is reduced compared to wild type.

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