Fig. 2. Bab1 and Bab2 have a BTB domain, a Psq-domain and an AT-hook-like motif. (A) Sequence similarity between Bab1 and Bab2 is restricted to the N-terminal BTB domain and the C-terminal BabCD. Sequence identity is indicated in percent. (B) Alignment of the BTB domains of Bab1 and Bab2. (C) Alignment of the BabCDs of Bab1 and Bab2. A Psq domain (underlined) and an AT-hook-like motif are contained within the BabCD. The BabCDs of Bab1 and Bab2 are encoded by three exons (black triangles indicate exon boundaries). (D) Comparison of the Psq domains of Bab1, Bab2, Tkr and Piefke, and the four Psq domains of the Psq protein. Residues conserved in all the domains are highlighted in black, less conserved residues are highlighted in gray. (E) Glutamine- (Q, gln) and histidine- (H, his) rich domains of Bab1 and Bab2.
