spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)


Fig. 7. GAL-GCN5 at blastoderm causes loss of silencing memory in larvae. (A) BHL4G4 expression in early embryos (left) and after germ band retraction (right) with no induction of the GAL-GCN5 protein (no hs). GAL-GCN5 induction at 2-3 hours does not affect the expression of BHL4G4. (B) When both GAL-GCN5 and hs-LexA-PC (hs-LexA-PC) proteins are produced at 2-3 hours, repression induced by hs-LexA-PC is prevented by GAL-GCN5, resulting in a strong ectopic expression in late embryos. In contrast, when {alpha}1-tubulin-LexA-PC ({alpha}1T-LexA-PC) is provided maternally, GAL-GCN5 does not interfere with PcG silencing. (C) When targeted to BHL4G4PRE in the 2-3 hours embryo, GAL-GCN5 does not interfere with repression in late embryos but results in loss of repression in larval imaginal discs. When the TRX level is reduced (trx), targeting GAL-GCN5 to BHL4G4PRE leads only to a very weak and partial derepression in larvae.





Right arrow Return to article