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Fig. 4. Induction of Eda (Ta) expression by WNT6 in skin epithelium. (A,B) WNT6-expressing cells stimulate Eda expression in whole skin explants (A) as well as in isolated epithelium (B). (C) 3T3 control cells failed to induce Eda. (D-H) None of the other signals tested (activin A, BMP4, EGF, FGF10 and SHH) had stimulatory effects on Eda expression. Scale bar: 200 µm.
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