Fig. 3. Expression of Pla2g4a in wild-type uteri during implantation and expression of implantation-specific genes in Pla2g4a^–/– uteri. (A) Comparison of expression of Pla2g4a with Ptgs1 and Ptgs2 in the mouse uterus during implantation. In situ hybridization of Pla2g4a, Ptgs1 and Ptgs2 on days 4-6 (09:00 hours) of pregnancy is shown. (B) In situ hybridization of Hegfl, Ptgs2, and Lif in uteri of wild-type and Pla2g4a^–/– mice on day 5 of pregnancy (10:00 hours). Note aberrant expression of Hegfl, Ptgs2 and Lif in the luminal epithelium and/or underlying stroma surrounding the blastocyst in Pla2g4a^–/– mice. Arrows indicate the location of blastocysts. ge, glandular epithelium; le, luminal epithelium; s, stroma; myo, myometrium.

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