Fig. 9. Integrin ß8 is expressed in periventricular cells of the embryonic brain. (A,B) Whole-mount in situ hybridization analyses shows integrin ß8 mRNA expression in tissues surrounding the ventricles of E10.5 embryonic brain (A, antisense; B, sense). (C,D) Transverse sections of E12.5 brains hybridized with integrin ß8 antisense (C) or sense (D) probes showing localization of integrin ß8 to periventricular cells in the neuroepithelium. (E,F) Similar areas to those shown in C at E12.5 (C, box E and box F) are shown at a higher magnification in an E13.5 brain hybridized with an integrin ß8 antisense probe (E,F). Note the absence of integrin ß8 mRNA from the vascular cells of the brain (A) and inside of the brain area (C,E). Scale bar: 500 µm in C and D; 200 µm in E,F.
