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Fig. 1. Labelled melanoblasts in Dct-lacZ control embryos of different ages. (A) E11.5. (B) E12.5. (C) E13.5. (D) E14.5. (E) E15.5. (F) E16.5. (A,B) Labelled melanoblasts can be seen at high density flanking the neural tube and in the cervical region. (C) By E13.5, melanoblasts have begun to disperse ventrally, and a significant proportion of the body and face have been populated. (D) By E14.5, melanoblasts are more numerous and almost the entire embryo has been colonised, including the ventrum and crown of the head. (E,F) Melanoblasts continue to increase in number and begin to colonise hair follicles (E15.5-E16.5). Scale bars: 0.8 mm in B; 1.6 mm in D; 3.2 mm in F, respectively.





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