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Fig. 2. Examples of Dct-lacZ {leftrightarrow} non-transgenic chimaeric embryos. (Ai) Ventral view of an E12.5 chimaera with labelled melanoblasts in the face and tail. (Aii-Aiii) Right and left side views of the same embryo. (B) E12.5 chimaera showing a dilution of labelled melanoblasts between the limbs (marked by arrows). (Ci-Cii) Left and right sides of an E13.5 chimaera showing distinctive gaps (marked by arrows) lacking labelled melanoblasts between the limbs. (D) Head and face of an E15.5 chimaera showing labelled melanoblasts in the snout, pinna and around the eye. (E) E16.5 chimaera showing discrete patches of labelled melanoblasts.





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