Fig. 3. Endogenous Wnt signaling represses Da and Ac expression and bristle formation at the periphery of the eye. (A) Wild-type pupal eye (3h APF) stained for Wg (red) and Ac (green). (B) P[wg-lacZ] pupal eye stained for ß-gal (red) and Da (green). In both cases, Ac and Da expression is absent from the edge of eye, where Wg is expressed. The Da signal observed at the edge of the eye in B is from peripodal membrane staining. (C-E) Micrographs of adult fly heads containing clones of wg^CX4 (C), Df(2L)RF (D) or arm^25B (E). Inside the wg clone, bristles are still inhibited at the edge of the eye. In the Df(2L)RF or arm clones shown, bristles are found up to the edge of the eye. At the top of the arm clone, ectopic bristles are present but are out of focus. See Results for further description of the clonal analysis.

Return to article