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Fig. 3. Sequence of ElB and Noc and gene structure. (A) Alignment of the protein sequence of ElB, Noc and the two human homologs. The following domains are marked: activation domain (red), Groucho binding sequence (purple), cysteine-rich domain (green), Zn finger (blue) and proline-tyrosine rich domain (orange). (B) Gene structures of elB and noc, and the position of the EP and Gal4 elements. elB and noc are positioned in opposite transcriptional orientations, and the ATG codon of each positioned within the first exon. The imprecise excisions generated in elB and noc are shown.