Fig. 7. Effects of ephrin-B1-Fc on neural crest cell adhesion to fibronectin. (A) Cells were plated on surfaces coated with fibronectin plus Fc (10 µg/ml) or fibronectin plus ephrin-B1-Fc (10 µg/ml), as described in Materials and Methods. Ephrin-B1-Fc significantly increases adhesion of melanoblasts to fibronectin (A,C), but decreases the attachment of early outgrowths to fibronectin (A,B). Asterisks represent no significant difference between values (P<0.05). Early outgrowths (B). Melanoblasts (C).

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