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Fig. 10. Histological structure of the epiphyseal plate. (A,B) Haematoxylin and Eosin-stained histological section of P7 tibia, showing reduced length of proliferative and hypertrophic chondrocyte columns in the Fgfr2IIIc mutant. (C) Morphometric analysis: cell number in the chondrocyte columns. bc, bone collar; ep-oc, epiphysial ossification center; hc, hypetrophic chondrocyte zone; pc, proliferating chondrocyte zone; rc, resting chondrocyte zone; tr, trabecular bone; PZ, zone of proliferating chondrocytes; HZ, zone of hypertrophic chondrocytes.





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