Fig. 8. Noggin also rescues normal dorsoventral but incomplete anterior axes in m/z ß-catenin^– embryos. (A) Embryos depleted of both maternal and zygotic ß-catenin (m/z ß-catenin^–)were injected with noggin mRNA (1, 10 or 50 pg) into 1 ventral vegetal cell a the 8-cell stage together with lacZ mRNA, and they were then processed for X-gal staining and photographed at the tailbud stage (stage 30). (B) Sibling embryos of those shown in A at stage 40. An uninjected control is included for comparison. Although the dorsoventral axis is normal, there are severe deficiencies in anterior patterning and axial length. (C) m/z ß-catenin^– control embryos from this experiment.

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