Fig. 5. Gene expression induced by protein-soaked beads in the posterior palatal mesenchyme of wild-type embryos. (A,B) BMP4-soaked beads failed to induce the expression of Msx1 (A) and Bmp4 (B) itself in the posterior palatal mesenchyme. (C) Shh-soaked beads also failed to induce Bmp2 expression in the posterior palatal mesenchyme. (D-F) FGF8-soaked beads induced Pax9 expression in the posterior palatal mesenchyme (D), but failed to do so in the anterior palatal mesenchyme (E), when compared with controls in which BSA-soaked beads were implanted into the posterior palatal mesenchyme (F).

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