Fig. 7. Contribution of Hoxb4 neural fold-derived cells to facial development. At E6, in chimeric embryos engrafted with Hoxb4 transfected neural folds, quail cells that populate the nasofrontal area (A) contribute to nerve glia (B), become pericyte (arrows) in choroid membrane (C), and form a loose mesenchyme under the olfactory epithelium (D). At E8, in such embryos, the sella turcica remains the most rostral skeletal structure (E) in which the basipostsphenoid is of host mesodermal origin (F) and the basipresphenoid of quail mesectodermal origin (G) (same staining procedure as in Fig. 5I,J). In the first branchial arch (H), quail cells generate both Meckel’s (I) and articular (J) cartilages. Mc, Meckel’s cartilage; Ar, articular. Scale bar: 230 µm in A; 30 µm in B; 30 µm in C; 30 µm in D; 375 µm in E; 10 µm in F; 10 µm in G; 600 µm in H; 12 µm in I; 12 µm in J.

Return to article