Fig. 6. Interval mapping of the modifier locus in the N2 analysis. Chromosome 2 (A), chromosome 10 (B) and chromosome 18 (C). The vertical and horizontal axes display LOD scores and the relative positions of the markers along the chromosomes from centromere (left) to telomere (right) in cM, respectively (determined by QTL cartographer). Two broken horizontal lines depict the LOD scores (1.9 and 3.3), which represent suggestive and significant linkages (Lander and Kruglyak, 1995), respectively. Red lines represent values obtained from mutant embryos displaying phenotypes of no mandible, small mandible and normal mandible. The most likely position for each locus, determined by its two LOD support intervals, is indicated by the black bar above the plot (B,C).

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