Fig. 5. Expression of three type A Dlx genes (Dlx2, Dlx5 and Dlx3; A-C) and one type B Dlx gene (Dlx1; D) in E10.5 mouse embryos shown by whole-mount in situ hybridization. The top pictures show a lateral view of the entire embryo (A-D); the bottom pictures show frontal views of dissected branchial arches. Expression of the Dlx genes is absent from the medial-most regions (these regions are under the control of the Msx and other genes). (E) Schematic lateral view of an E10.5 mouse embryo, highlighting craniofacial primordia that are under the control of the Dlx genes: the jaw, otic and olfactory apparatus (the branchial arches, otic vesicle and olfactory placode, respectively). The color wheel in the bottom right corner defines colors that correspond to the expression of type A Dlx genes: Dlx2, Dlx3 and Dlx5. These colors are used in the schema to describe the expression of these genes in the ectomesenchyme of the branchial arches and the ectoderm of the olfactory placode/pit and otic vesicle, respectively.

Return to article