Fig. 9. (A) Western immunoblots for Bcl-2 and Bcl-xL, in day-1 and day-10 lactating mammary glands from wild-type and transgenic mice. Three representative animals are shown and the bar chart in C illustrates quantitative analysis of the data. (B) Endonucleosomal ladders in mammary gland DNA preparations. Lanes 1-4 show ethidium bromide detection, and lanes 5-10 show [³²P]dCTP-end labelling. Lane 1, wild type, day 2 of lactation; lane 2, transgenic, day 2 of lactation; lane 3, wild type, day 10 of lactation; lane 4, day 2 of involution (positive control). Lanes 5-7 are samples from 3 representative day-1 lactating transgenic mice and lanes 8-10 are samples from 3 representative day-1 lactating wild-type mice. (C) Quantitative analyses for values on day 1 of lactation. White bars, transgenics, black bars, wild type. Values are mean ± s.e.m. for 5-6 mice per group. *P<0.05, **P<0.01 compared with wild-type mice.

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