Fig. 2. The cytological and physical localization of ix. (A) Deficiency mapping of ix. The boxes indicate the region of the chromosome deleted for each deficiency chromosome (reported breakpoints in parentheses after deficiency names). The black boxes represent the deficiencies that fail to complement ix, and the white boxes represent the deficiencies that complement the loss-of-function alleles of ix. (B) Chromosomal walk spanning ix. Cosmid and phage clones spanning the cytological region 47F are indicated by lines. The relevant deficiency breakpoints are indicated above the DNA walk, and the probes used for RFLP mapping are indicated below the DNA clones. Map in A, reproduced (with permission) from Bridges and Bridges (Bridges and Bridges, 1939).

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