Fig. 8. The synaptic zone remains broader in Musk^-/-; MCK-Musk and Musk^-/-; MCK-MMT adult mice. As a consequence of delayed expression from the MCK gene, the axon termination zone is wider in MCK^-/-; MCK-Musk and MCK^-/-; MCK-MMT embryos than in wild-type embryos, and this broader termination zone is retained in adult mice. Wholemounts of diaphragm muscles from 3-week-old mice were stained with antibodies to neurofilament (NF) and synaptophysin (Syn) to label axons and presynaptic nerve terminals (green), and with Texas-Red -Bungarotoxin (TR--BGT) to label AChRs (red).

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