Fig. 5. Visual projections are altered in adult mutant mice. Frontal sections of adult wild type (A,B) and Vax2–/– (C,D) brains at the mid-superior colliculus. (A,C) Phase contrast views of the sections presented in B,D, respectively. DiI was injected into the ventral retina of adult wild-type and mutant mice. (B) In wild-type mice, DiI-labelled axons project to the entire medial region (thick arrow) of the contralateral superior colliculus and to patches of the stratum opticum of the ipsilateral superior colliculus (thin arrows). (D) Note the absence of the ipsilateral and most medial contralateral projections in the superior colliculus of mutant mice. SC, superior colliculus. Scale bar: 150 µm.
