Fig. 7. Misexpression of Math3 and NeuroD with retrovirus. (A) Retroviral vectors. GFP, green fluorescent protein; IRES, internal ribosomal entry site; LTR, long terminal repeat. (B) Retinal explants were prepared from E17.5 mouse embryos and infected with CLIG, CLIG-Math3, and CLIG-NeuroD. After 2 weeks, the explants were subjected to immunohistochemistry using anti-GFP antibody. (C) Ratios of retinal cell types infected with CLIG, CLIG-Math3 and CLIG-NeuroD. Rod genesis is increased while gliogenesis is inhibited by Math3 and NeuroD.
