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Fig. 3. vab-7 represses unc-4 in DB motoneurones. (A) Wild-type expression of unc-4::GFP in DA motoneurones of an L1 larva. (B) unc-4::gfp is ectopically expressed in the DBs in a vab-7(e1562) background. (C) Wild-type expression of unc-4::lacZ in DAs of an L1 larva (D) unc-4::lacZ is repressed in DAs of an L1 larvae by ectopic VAB-7 expession from unc-3::vab-7 transgene (weIs10). ß-Galactosidase staining is retained in a cluster of neurones at the anterior end of the VNC in which unc-3::vab-7 is not expressed Anterior is towards the left in all panels. Scale bars: in A, 10 µm in A,B; in C, 2.5 µm in C,D.





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