Fig. 5. Ectopic VAB-7 is sufficient to promote posterior axonal outgrowth in cholinergic motoneurones. Dorsal views of unc-17/cha-1::gfp staining of DA, DB and AS axons entering the DNC of adult animals. (A) DA and AS motor axons project anteriorly in the wild type; DB axons are posteriorly directed. (B) An unc-3::vab-7 transgene (weIs10) drives ectopic VAB-7 expression in ventral cord motoneurones and redirects AS and DA axons to adopt a posterior trajectory. Yellow arrow points to DNC. Anterior is towards the left. Scale bar: 15 µm.
