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Fig. 8. Electron microscopic sections of wild-type and TLF–/– seminiferous tubules. (A-I) High magnification views of defective acrosome formation. (J) Wild-type and (K) mutant cell showing position of organelles. (A) Normal acrosome in wild-type spermatids; (B-E) defective acrosome in round spermatids; (F-G) acrosome in early wild-type or mutant elongating spermatids; (H-I) defective acrosome in late step 13 wild-type or mutant elongating spermatids. AG, acrosomal granule; G, Golgi; N, nucleolus; V, vacuole; C, chromocenter; A, acrosome. B shows a close-up of the acrosome of the cell shown in K. A,C-G: 4000x magnification; B,H-K, 5000x magnification.





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