Fig. 6. Differential BMP dependence of dorsal Phox2a-positive LC neurones, Lhx2a-positive neurones and ventral GATA2 neurones in r1. Lhx2a-positive neurones (A, arrows) have a similar expression pattern to Phox2a-expressing LC neurones (C, arrows) during the early stages of chick r1 development (stage 22). Implantation of Noggin-producing CHO cells results in a complete loss of Lhx2a expression at stage 22 (B, arrow), while in a parallel section, Phox2a-positive cells are present in the dorsal midline (D, arrow). By contrast, at stage 22, the GATA2 expression pattern of ventral neurones (E, arrow) is unchanged after Noggin-treatment (F, arrow).
