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Fig. 8. DMBS genetically interacts with zip and with mutations in the components of the Rho signaling pathway. A partial defect of zip causes the malformed adult wing phenotype with a gradation in severity. (A) A wild type wing. (B,C) Wings of the zipEbr/zip02957 transheterozygotes. (D) Percentages of malformed wings in the flies with genotypes indicated on the left side of the panel. Heterozygosity for DMBSE1 significantly suppressed wing defects. (E) A model for the pathways regulating nonmuscle myosin II activation. See the text for the detail.





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