
Fig. 2. Phylogenetic tree of Pax genes. The tree was derived from the homeodomain and flanking regions of representatives from different Pax classes (indicated on the right), using the Neighbor-joining method. Sequences reported in this paper are in bold. Bootstrap percentage values (1000 replicates) are shown over the corresponding nodes. All branch lengths are proportional to the distances between sequences. The tree was rooted using Hydra PaxB as an outgroup. The analysis includes: human Pax 3, 4, 6 (Aniridia) and 7; mouse Pax3, 4, 6 and 7; zebrafish Pax6; sea urchin suPax6; chordate PmPax6 and Amphi-Pax6; mollusc Lo-Pax6; Drosophila ey and toy; C. elegans Cevab-3; nemertine LsPax6; planarian GtPax6A and GtPax6B, DjPax6A and DjPax6B; and cnidarian PaxC and Hl PaxB.