Fig. 1. Cell lineages of the T cell in wild-type and tlp-1 hermaphrodites. (A) Wild-type hermaphrodite T cell lineage. The fates of many different cells in this lineage can be distinguished by nuclear morphology using DIC microscopy (Sulston and Horvitz, 1977; Herman and Horvitz, 1994). The hyp7 cells T.aa, T.apaa and T.apap join the hypodermal syncytium, but T.apaa has a smaller nucleus and is designated hyp7(sm). PHso1, PHso2, PVW, PHC and PLN have similar nuclear morphologies. x indicates apoptosis. The seam cell (se) is a specialized hypodermal cell. (B) We analyzed T cell lineages on both sides of three ny14, two bx85 and two mh17 mutants (14 total T cell lineages). Arrows indicate that a particular cell was sometimes observed to divide in a subset of the lineages. Six ny14 lineages and one bx85 lineage had the T cell division pattern that is shown in the upper left; however, in two ny14 lineages and one bx85 lineage, the T.app cell divided once to generate two hypodermal cells. Two mh17 lineages had T cell division pattern shown in the upper right; however, in one, the T.pa cell divided to generate two hypodermal cells. Two bx85 lineages had the T cell division pattern shown in the lower left; however, in one, the T.ap cell divided to generate two hypodermal cells. Two mh17 and one bx85 had the T cell division pattern shown in the lower right corner; however, in one of the mh17 lineages, the T.pa cell did not divide and generated a hyp cell.
