Fig. 6. Snail represses potential inhibitors of Notch signaling. Wild-type (A,B) and Tollrm9/Tollrm10 (C,D) mutant embryos were stained with either a Delta (A,B) or T3 hybridization probe (C,D). Embryos have completed cellularization and are oriented with anterior to the left. (A,B) Delta is expressed in lateral and dorsal regions of wild-type embryos (A). Staining is excluded from the ventral mesoderm, possibly by the Snail repressor as the Delta pattern is derepressed in sna–/sna– mutant embryos (not shown). The stripe2-snail transgene (B) causes a slight weakening of the normal Delta pattern (arrowhead). (C,D) T3 is expressed in a series of stripes along the entire dorsoventral axis of Tollrm9/Tollrm10 mutant embryos (C). The stripe2-snail transgene (D) creates a gap in the T3 expression pattern (arrowhead).
