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Fig. 3. Expression of endothelial (VEGFR1, VEGFR2 and VEZF) and haematopoietic (EKLF) markers is disturbed in Vegflo/lo embryos. Whole-mount in situ hybridisation for the marker gene expression was performed on 8.0 and 9.0 dpc wild-type (+/+) and Vegflo/lo (–/–) embryos. Note the presence of intersomitic vessels sprouting from the dorsal aorta in 9.0 dpc Vegflo/lo (–/–) embryos that hybridised to the VEGFR2 probe.





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