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Corrigendum for Fisher et al., Development 129 (6) 1307-1315.

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eFGF is required for activation of XmyoD expression in the myogenic cell lineage of Xenopus laevis

(2002). Development 129, 1307-1315

Fig. 1B of this paper shows the expression of Xmyf5 and not XmyoD as stated. As a consequence, the first paragraph of the Results section is inaccurate. The correct figure and text are given here and in the online versions.

View larger version (44K): [in this window] [in a new window]   Fig. 1. The normal expression patterns of eFGF and XmyoD showing co-expression in the early mesoderm. Whole-mount in situ hybridisation showing expression of (A) eFGF at stage 10, (B) XmyoD at stage 10 and (C) XmyoD at stage 10 (+). Expression of XmyoD across the dorsal midline is rapidly excluded as Spemann’s organiser signalling is established.

eFGF and XmyoD are co-expressed in the early mesoderm
As discussed above, there is evidence to suggest a role for FGF signalling during myogenesis. We show that the expression domains of XmyoD and eFGF overlap in the early mesoderm. Both genes are initially co-expressed within a region that encompasses much of the mesoderm (Fig. 1).

ADDITIONAL INFORMATION

The authors have supplied additional data to illustrate that the expression of these two genes is similar at this stage, as shown below.

View larger version (83K): [in this window] [in a new window]   The normal expression of Xmyf5 and XmyoD at early gastrula stage 10. Whole-mount in situ hybridisation shows that Xmyf5 expression (A) is strong dorsally and spans the dorsal midline. XmyoD (B) is expressed more evenly throughout the marginal zone but is excluded from the dorsal midline.

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This Article Figures Only Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Fisher, E. M. Articles by Pownall, M. E. Search for Related Content PubMed Articles by Fisher, E. M. Articles by Pownall, M. E. Social Bookmarking                         What's this?