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Fig. 3. Brn3a-binding sites are highly conserved in the mouse and human sensory enhancer regions. Pairwise alignment of the mouse and human Brn3a sequences reveals several regions of upstream homology, the most extensive of which encompasses a cluster of Brn3a binding sites (red), and an octamer site (blue). The y-axis represents the percent of base pair identity within a moving window of 120 bases, at intervals of 40 bases. The designated map positions are for the mouse sequence and are specified relative to the most frequently used transcription start site (red G residue in the right-hand box).





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