Fig. 7. Adult phenotypes (A-C) and imaginal disc expression patterns (D-G) caused by the co-expression of wg and vg in clones in the wing imaginal disc. Adult clones are labelled with f and delimited by a broken red line. In the imaginal discs, wg-vg clones are associated with GFP. Scale bars: 0.1 mm. (A) wg-vg clones in the wing blade may induce the appearance of tubular outgrowths. Notice the large non-autonomous growth induced by the clone. The age of clone initiation is 60±12 hours AEL. (B) Clones situated near the wing margin do not induce outgrowths. The age of clone initiation is 60±12 hours AEL. (C) In the notum, all the cells of wg-vg clones (delimited by a broken red line) differentiate into wing margin sensory elements and non-autonomously induce cuticular transformation to wing blade (delimited by a broken black line). The age of clone initiation is 36±12 hours AEL. (D) wg-vg clones (GFP) induced anywhere within the imaginal disc activate autonomously and non-autonomously the expression of vg (red; white arrowhead). The age of clone initiation is 60±12 hours AEL. (E) wg-vg (GFP) clones show heterogeneous or low levels of wg expression (red; white arrowheads). The age of clone initiation is 60±12 hours AEL. (F) wg-vg clones (GFP) autonomous and non-autonomously activate the expression of nub (red) anywhere in the imaginal disc. Notice that the non-autonomous expression of nub (red) is detected in cells surrounding the clone at long distances. The age of clone initiation is 60±12 hours AEL. (G) wg-vg clones (GFP) in the wing blade autonomously and non-autonomously repress bs (red; white arrowhead) expression, but in the wing hinge or in the notum, bs is autonomously repressed and non-autonomously induced. The age of clone initiation is 60±12 hours AEL.

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