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Fig. 6. Changes in cell death in developing wild-type and TAG/F3 mice
cerebella. (A) TUNEL staining in lobule IX of wild-type (WT) and
TAG/F3 mice cerebellum at postnatal day 3. Arrows indicate the
TUNEL-positive elements, higher magnification views of which are shown in the
insets. Scale bar: 100 µm. (B) Histogram showing the density of apoptotic
cells in cerebellar sections from both wild type and TAG/F3 mice from
P0 to P8. Asterisks refer to statistical significance of the differences
observed between the two genotypes. ***P=0.001. (C) Sample
of TUNEL-stained elements (arrows) in high density primary cerebellar cultures
from postnatal day 3 wild-type and TAG/F3 mice (Bar=10 µm).