Fig. 8. (A) Developmental changes of Purkinje neurons in wild-type (a,c,e,g,i,k,m) and TAG/F3 (b,d,f,h,j,l,n) mice as revealed by calbindin immunostaining at postnatal day (P) 0 (a-d), P3 (e-h), P8 (i,j), P11 (k,l) and P16 (m,n) in thin (5 µm) paraffin sections from cerebellar cortex. High-power images in c and d correspond to lobules II and III, and images in g-n correspond to lobule VIII. Scale bars: (a,b,e,f) 200 µm; (c,d,g-n) 40 µm. (B) Phenotype of Purkinje cells dendritic tree shown in thick (20 µm) cryostat sections from wild type (WT) and TAG/F3 mice cerebella (lobule IX) labelled with calbindin antibodies at postnatal day 6. Bar: 20 µm.

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