Fig. 1. p27^Xic1 is expressed in cells destined to become primary neurones. Whole-mount in situ hybridisation at indicated stages show expression of p27^Xic1 (A-C,G,I) or XMyT-1 (D-F,H). Except for G, figures show a dorsal view with anterior towards the bottom. Both p27^Xic1 and XMyT-1 are found in lateral, intermediate and medial stripes of primary neurones, placodes (arrows) and the trigeminal ganglia (arrowheads). (G) Stage 13 embryos show p27^Xic1 staining in the epidermis. (H) Double in situ hybridisation demonstrates overlap between p27^Xic1 (purple) and XMyT-1 (light blue). (I) Vibratome section of a stage 15 embryo shows p27^Xic1 expression in the myotome (My), notochord (Not) and primary neurone precursors (PNP) in the sensorial layer of the neural plate (arrow).

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