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Fig. 6. GDNF heterozygous mice have a reduced rate of ENS neuronal precursor proliferation. (A,B) BrdU (FITC) and PGP9.5 (Cy3) double labeling in the E12 gut. The red arrow indicates a PGP9.5-positive cell that had incorporated BrdU. Blue arrows indicate PGP9.5-positive cells that have not incorporated BrdU. (C) Quantitative analysis of the rate of ENS neuronal precursor proliferation. *P=0.01. Scale bar: 20 µm.





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