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Development 130, e1202 (2003)
Copyright © 2003 The Company of Biologists Limited


IN THIS ISSUE

Dendrite elaboration in mushroom bodies


Mushroom bodies (MBs) are bilaterally symmetrical, fly brain structures required for olfactory learning and memory. Each one is derived from four neuroblasts and consists of ~2000 Kenyon cells (KCs) that project dendrites into the calyx where olfactory inputs are received and processed. Zhu et al. have used a clonal system to visualize neurons in whole-mount brain preparations to address key questions about the organization of these dendrites, such as: do KC dendrites of different clonal origin occupy the same or different territories in the larval and adult calyx? Their results on p. 2603 shed light on these important questions. For example, they find that MB dendrites of different clonal origins, although well mixed in larval brains, become restricted to distinct calycal spaces in adults, and that various subtypes of MB dendrites contribute differentially to calycal regions.


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Related articles in Development:

Development of the Drosophila mushroom bodies: elaboration, remodeling and spatial organization of dendrites in the calyx
Sijun Zhu, Ann-Shyn Chiang, and Tzumin Lee
Development 2003 130: 2603-2610. [Abstract] [Full Text]  




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