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Fig. 6. PINCH function is essential for adhesion between wing epithelial sheets. (A) Production of stck17 homozygous clones in wing tissue leads to blister formation. (B-D) Confocal micrographs of a developing wing disc (~45 hours after puparium formation). (B) ßPS integrin protein is enriched at the basal junctions between the two epithelial layers (arrow). (C) PINCH protein is also expressed in the developing wing, and displays a similar subcellular distribution (arrow). (D) Merge of B and C.





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