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Fig. 8. Expression of esc in Df(2R)achi1 mutants. (A) RT-PCR analysis on RNA samples from wild-type and Df(2R)achi1 mutant testes reveal that esc is amongst the genes showing enhanced transcript abundance in Df(2R)achi1 mutants, other enhanced transcripts include haywire and Taf24. (B) Anti-Esc immunolabelling on wild-type testes. Esc accumulates in nuclear speckles during primary spermatocyte differentiation. (C) Anti-Esc immunolabelling on Df(2R)achi1 testis. Esc is clearly expressed and demonstrates the expansion of the early primary spermatocyte population. Nuclear speckles do not form.





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