QUICK SEARCH:   [advanced] Author: Keyword(s):
Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Related articles in Development Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content Social Bookmarking                         What's this?

F-actin: shaping plant and animal cells

Specific cell types are generated partly by differential growth (when certain cell regions rapidly expand). In animal cells, this requires the actin cytoskeleton. Mathur et al. now report, on p. 3137, that an actin-based mechanism might also regulate differential growth in plants, with their discovery that a mutation in the plant orthologue of ARPC5 causes random cell expansion and aberrant cell shape in Arabidopsis CROOKED mutants. ARPC5 is a subunit of the ARP2/3 complex – an actin polymerization modulator in many organisms that generates fine F-actin arrays. By studying polarized cells in mutant and normal plants, the authors found that localized cell expansion occurs only where fine F-actin is maintained, implicating F-actin density as a likely determinant of cell shape. Importantly, the rescue of CROOKED cells with human ARPC5 provides the first evidence that this complex is functionally conserved in higher plants.

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

Related articles in Development:

Arabidopsis CROOKED encodes for the smallest subunit of the ARP2/3 complex and controls cell shape by region specific fine F-actin formation

Jaideep Mathur, Neeta Mathur, Victor Kirik, Birgit Kernebeck, Bhylahalli Purushottam Srinivas, and Martin Hülskamp
Development 2003 130: 3137-3146. [Abstract] [Full Text]  

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Related articles in Development Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content Social Bookmarking                         What's this?