Fig. 3. Laminin A is associated with neurons. Immunofluorescence micrograph of nid-1(+) (A,B) and nid-1(ur41) (C,D) animals that express GFP in right fascicle axons of the ventral nerve cord were co-stained with anti-GFP (A,C) and anti-laminin A (B,D) antiserum. In wild type, there is an average of 54 axons in the right fascicle and six in the left (Hedgecock et al., 1990). (C) In nid-1(ur41) mutants, several axons from the right fascicle are mispositioned to the left fascicle (Kim and Wadsworth, 2000). (D) Laminin A associates with the mispositioned axons in the left fascicle (arrows). Ventral aspect. The midline is defined by the vulva (^*) and midline motor neuron cell bodies (arrowheads in C). Anterior is towards the left, dorsal towards the top.

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