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Fig. 7. The effect of overexpression of components and dominant-negative components of the Wnt signalling pathway on fibre-type differentiation in vitro. (A-J) Fluorescent images showing terminally differentiated myogenic cells that have been visualized using antibody A4.1025, which recognizes slow and fast MyHCs (A-D,I,J, green), and antibody A4.840, which recognizes slow MyHC (E-H, red) in stage 21/22 micromass cultures that have been infected with control RCAS virus (A,E,I) or retroviruses expressing Dsh{Delta}PDZ (B,F), {Delta}Lef1 (C,G,J) or activated CamKII (D,H). Scale bars: 100 µm in A-H; 25 µm in I,J.





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