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Fig. 7. The effect of overexpression of components and dominant-negative components
of the Wnt signalling pathway on fibre-type differentiation in vitro. (A-J)
Fluorescent images showing terminally differentiated myogenic cells that have
been visualized using antibody A4.1025, which recognizes slow and fast MyHCs
(A-D,I,J, green), and antibody A4.840, which recognizes slow MyHC (E-H, red)
in stage 21/22 micromass cultures that have been infected with control RCAS
virus (A,E,I) or retroviruses expressing Dsh
PDZ (B,F),
Lef1
(C,G,J) or activated CamKII (D,H). Scale bars: 100 µm in A-H; 25 µm in
I,J.