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Fig. 5. Steroidogenic cells migrate from the anterior region of the mesonephros
into the Wnt4-/- XX gonad. Gonads from
Wnt4-/- XX 11.5-12.5 dpc embryos were incubated with
mesonephroi from Cyp11a1:lacZ 11.5-12.5 dpc embryos and stained for
ß-galactosidase activity. (Top) The anterior region of the mesonephros
was included in the co-culture, and (bottom) the anterior region of the
mesonephros was removed. The lines indicate the boundary between gonad and
mesonephros in the co-cultures.