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Fig. 9. A model for Sog/integrin interactions in the wing. The primary proposed
function of 
PS1ßPS integrin in modulating Sog activity in the
wing. In wild-type wings, ß integrin heterodimers enhance the
delivery or diffusion of an active Bmp inhibitory form of Sog into the provein
domain. This non-autonomous source of Sog limits peak Bmp signaling to the
center of the provein territory. In the absence of PS1ßPS, a
repulsive form of Sog protein is unable to enter the provein territory, while
a remaining unaffected Bmp promoting Sog activity (not shown) attracts the
vein towards the mutant clone.
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