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Fig. 4. A ces-1(lf) mutation is unable to suppress the NSM sister cell survival caused by hlh-2(RNAi) or hlh-3(RNAi). (A) A ces-1(lf) mutation is not able to suppress the NSM sister cell survival induced by hlh-2(RNAi). NSM sister cell survival was analysed as described in the Materials and Methods (n=96-142). dsRNA was delivered by feeding. hlh-6 dsRNA was used for control RNAi. The complete genotype of the animals analysed was as follows hlh-2(RNAi); bcIs25, ces-1(n703 n1434lf); hlh-6(RNAi); bcIs25, ces-1(n703 n1434lf); hlh-2(RNAi); bcIs25. (B) A ces-1(lf) mutation is not able to suppress the NSM sister cell survival induced by hlh-3(RNAi). NSM sister cell survival was analysed as described in the Materials and Methods (n=174-218). dsRNA was delivered by injection. hlh-6 dsRNA was used for control RNAi. The complete genotype of the animals analysed was as follows: hlh-3(RNAi); bcIs25, ces-1(n703 n1434lf); hlh-6(RNAi); bcIs25, ces-1(n703 n1434lf); hlh-3(RNAi); bcIs25. Error bars represent the standard deviation of the average percent survival obtained for the progeny of different injected animals.





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