Fig. 7. Disturbing Xlim-1/Ldb1 stoichiometry affects their axis inducing activity. Ldb1 dose-dependently suppresses axis duplication by Xlim-1, which is rescued by co-expression of a higher dose (1 ng) of Xlim-1. Embryos injected with the mRNAs indicated were scored for axis development at the tailbud stage as in Fig. 3A. ß-globin (2.0 ng/embryo) serves as a negative control. n, total number of injected embryos; expt, number of independent experiments. Amounts of mRNAs injected are indicated in parentheses (ng/embryo).

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