Fig. 6. Percentage donor chimerism in the blood of recipient mice transplanted with fetal liver or adult marrow cells. (A) Fetal liver donor cells expressing Kit, CD34 and CD41 (+++) demonstrated minimal but detectable repopulating ability in the competitive repopulating assay, however, cells expressing Kit, CD34, but not CD41 (++-) demonstrated high repopulating ability. (B) Adult marrow cells expressing Kit, CD34, and CD41 (+++) or minus CD41 (++-) demonstrated minimal but detectable repopulating ability in the competitive repopulation assay. Marrow cells with the phenotype Kit⁺CD34^-CD41⁺ (+-+) demonstrated slightly greater repopulating ability than the +++, or ++- cells (P>0.05). Marrow cells with the phenotype Kit⁺CD34^-CD41^- (+-) demonstrated significantly greater (P<0.05) repopulating ability than all other sorted donor cell populations.

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