Fig. 1. Neurochemically identified subpopulations of radial glia in wild-type and reeler telencephalon. Frontal vibratome sections of wild-type (A,C,E-G) and reeler (B,D) telencephalon stained for Blbp (A-D,F,G), Rc2 (A-D) or reelin (E-G). A-D show sections of embryonic day (E) 16 wild-type (A,C) and reeler (B,D) cortex stained for Rc2 (red) and Blbp (green) as indicated in the micrographs. A-D show maximum intensity pictures (50 µm), A',A'' and B',B'' depict single optical sections (5 µm). Note that Rc2-immunoreactivity is similar, but the Blbp-immunoreactivity is strongly reduced in the reeler cortex, whereas no difference is seen in the GE. E depicts a low power view of reelin-immunoreactive cells in the telencephalon at E14. The broken line indicates the outline of the ventricle and border between cerebral cortex (Ctx) and ganglionic eminence (GE). (F,G) High power views of the cortex (F) and ventral telencephalon (G), as indicated by the white boxes in E. Note the close vicinity of reelin-immunoreactive neurons (red, examples indicated by arrows) and the Blbp-immunopositive endfeet of radial glial cells (green) from the cerebral cortex (F), but not from the GE (G).

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